Cargando…
A novel thermostable beetle luciferase based cytotoxicity assay
Cytotoxicity assays are essential for the testing and development of novel immunotherapies for the treatment of cancer. We recently described a novel cytotoxicity assay, termed the Matador assay, which was based on marine luciferases and their engineered derivatives. In this study, we describe the d...
Autores principales: | Choi, Sunju, Matta, Hittu, Gopalakrishnan, Ramakrishnan, Natarajan, Venkatesh, Gong, Songjie, Jeronimo, Alberto, Kuo, Wei-Ying, Bravo, Bryant, Chaudhary, Preet M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113442/ https://www.ncbi.nlm.nih.gov/pubmed/33976304 http://dx.doi.org/10.1038/s41598-021-89404-z |
Ejemplares similares
-
A Fast and Sensitive Luciferase-based Assay for Antibody Engineering and Design of Chimeric Antigen Receptors
por: Natarajan, Venkatesh, et al.
Publicado: (2020) -
Development and characterization of a novel luciferase based cytotoxicity assay
por: Matta, Hittu, et al.
Publicado: (2018) -
Narciclasine, an isocarbostyril alkaloid, has preferential activity against primary effusion lymphoma
por: Gopalakrishnan, Ramakrishnan, et al.
Publicado: (2020) -
A novel luciferase-based assay for the detection of Chimeric Antigen Receptors
por: Gopalakrishnan, Ramakrishnan, et al.
Publicado: (2019) -
Immunomodulatory drugs target IKZF1-IRF4-MYC axis in primary effusion lymphoma in a cereblon-dependent manner and display synergistic cytotoxicity with BRD4 inhibitors
por: Gopalakrishnan, Ramakrishnan, et al.
Publicado: (2015)