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CopyCatchers are versatile active genetic elements that detect and quantify inter-homolog somatic gene conversion
CRISPR-based active genetic elements, or gene-drives, copied via homology-directed repair (HDR) in the germline, are transmitted to progeny at super-Mendelian frequencies. Active genetic elements also can generate widespread somatic mutations, but the genetic basis for such phenotypes remains uncert...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113449/ https://www.ncbi.nlm.nih.gov/pubmed/33976171 http://dx.doi.org/10.1038/s41467-021-22927-1 |