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Single nucleus multi-omics regulatory landscape of the murine pituitary
To provide a multi-omics resource and investigate transcriptional regulatory mechanisms, we profile the transcriptome, chromatin accessibility, and methylation status of over 70,000 single nuclei (sn) from adult mouse pituitaries. Paired snRNAseq and snATACseq datasets from individual animals highli...
Autores principales: | Ruf-Zamojski, Frederique, Zhang, Zidong, Zamojski, Michel, Smith, Gregory R., Mendelev, Natalia, Liu, Hanqing, Nudelman, German, Moriwaki, Mika, Pincas, Hanna, Castanon, Rosa Gomez, Nair, Venugopalan D., Seenarine, Nitish, Amper, Mary Anne S., Zhou, Xiang, Ongaro, Luisina, Toufaily, Chirine, Schang, Gauthier, Nery, Joseph R., Bartlett, Anna, Aldridge, Andrew, Jain, Nimisha, Childs, Gwen V., Troyanskaya, Olga G., Ecker, Joseph R., Turgeon, Judith L., Welt, Corrine K., Bernard, Daniel J., Sealfon, Stuart C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113460/ https://www.ncbi.nlm.nih.gov/pubmed/33976139 http://dx.doi.org/10.1038/s41467-021-22859-w |
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