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Neural network aided approximation and parameter inference of non-Markovian models of gene expression

Non-Markovian models of stochastic biochemical kinetics often incorporate explicit time delays to effectively model large numbers of intermediate biochemical processes. Analysis and simulation of these models, as well as the inference of their parameters from data, are fraught with difficulties beca...

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Detalles Bibliográficos
Autores principales: Jiang, Qingchao, Fu, Xiaoming, Yan, Shifu, Li, Runlai, Du, Wenli, Cao, Zhixing, Qian, Feng, Grima, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113478/
https://www.ncbi.nlm.nih.gov/pubmed/33976195
http://dx.doi.org/10.1038/s41467-021-22919-1