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Following replicative DNA synthesis by time-resolved X-ray crystallography
The mechanism of DNA synthesis has been inferred from static structures, but the absence of temporal information raises longstanding questions about the order of events in one of life’s most central processes. Here we follow the reaction pathway of a replicative DNA polymerase using time-resolved X-...
Autores principales: | Chim, Nicholas, Meza, Roman A., Trinh, Anh M., Yang, Kefan, Chaput, John C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113479/ https://www.ncbi.nlm.nih.gov/pubmed/33976175 http://dx.doi.org/10.1038/s41467-021-22937-z |
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