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SARS-CoV-2 gene content and COVID-19 mutation impact by comparing 44 Sarbecovirus genomes

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Despite its clinical importance, the SARS-CoV-2 gene set remains unresolved, hindering dissection of COVID-19 biology. We use comparative genomics to provide a high-confidence protein-coding gene set, characterize evolutionary constraint, and prioritize functional mutations. We select 44 Sarbecoviru...

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Detalles Bibliográficos
Autores principales:	Jungreis, Irwin, Sealfon, Rachel, Kellis, Manolis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113528/ https://www.ncbi.nlm.nih.gov/pubmed/33976134 http://dx.doi.org/10.1038/s41467-021-22905-7

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