Knockout RAGE alleviates cardiac fibrosis through repressing endothelial-to-mesenchymal transition (EndMT) mediated by autophagy

Endothelial-to-mesenchymal transition (EndMT) has been shown to contribute to cardiac fibrosis and heart failure (HF). Recent studies have demonstrated that EndMT is regulated by autophagy, and we previously showed suppression of excessive autophagy and alleviation of cardiac fibrosis in HF mice wit...

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Detalles Bibliográficos
Autores principales: Zhang, Lu, He, Jiaqi, Wang, Junyan, Liu, Jing, Chen, Zixin, Deng, Bo, Wei, Lan, Wu, Hanqin, Liang, Birong, Li, Huan, Huang, Yusheng, Lu, Lu, Yang, Zhongqi, Xian, Shaoxiang, Wang, Lingjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113558/
https://www.ncbi.nlm.nih.gov/pubmed/33976108
http://dx.doi.org/10.1038/s41419-021-03750-4

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