Identification of poly(ADP-ribose) polymerase 9 (PARP9) as a noncanonical sensor for RNA virus in dendritic cells

Innate immune cells are critical in protective immunity against viral infections, involved in sensing foreign viral nucleic acids. Here we report that the poly(ADP-ribose) polymerase 9 (PARP9), a member of PARP family, serves as a non-canonical sensor for RNA virus to initiate and amplify type I int...

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Detalles Bibliográficos
Autores principales: Xing, Junji, Zhang, Ao, Du, Yong, Fang, Mingli, Minze, Laurie J., Liu, Yong-Jun, Li, Xian Chang, Zhang, Zhiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113569/
https://www.ncbi.nlm.nih.gov/pubmed/33976210
http://dx.doi.org/10.1038/s41467-021-23003-4

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