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A neural basis for brain leptin action on reducing type 1 diabetic hyperglycemia
Central leptin action rescues type 1 diabetic (T1D) hyperglycemia; however, the underlying mechanism and the identity of mediating neurons remain elusive. Here, we show that leptin receptor (LepR)-expressing neurons in arcuate (LepR(Arc)) are selectively activated in T1D. Activation of LepR(Arc) neu...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113586/ https://www.ncbi.nlm.nih.gov/pubmed/33976218 http://dx.doi.org/10.1038/s41467-021-22940-4 |