YAP promotes the activation of NLRP3 inflammasome via blocking K27-linked polyubiquitination of NLRP3

The transcription coactivator YAP plays a vital role in Hippo pathway for organ-size control and tissue homeostasis. Recent studies have demonstrated YAP is closely related to immune disorders and inflammatory diseases, but the underlying mechanisms remain less defined. Here, we find that YAP promot...

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Detalles Bibliográficos
Autores principales: Wang, Dan, Zhang, Yening, Xu, Xueming, Wu, Jianfeng, Peng, Yue, Li, Jing, Luo, Ruiheng, Huang, Lingmin, Liu, Liping, Yu, Songlin, Zhang, Ningjie, Lu, Ben, Zhao, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113592/
https://www.ncbi.nlm.nih.gov/pubmed/33976226
http://dx.doi.org/10.1038/s41467-021-22987-3

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