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Integration of machine learning and genome-scale metabolic modeling identifies multi-omics biomarkers for radiation resistance

Resistance to ionizing radiation, a first-line therapy for many cancers, is a major clinical challenge. Personalized prediction of tumor radiosensitivity is not currently implemented clinically due to insufficient accuracy of existing machine learning classifiers. Despite the acknowledged role of tu...

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Detalles Bibliográficos
Autores principales: Lewis, Joshua E., Kemp, Melissa L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113601/
https://www.ncbi.nlm.nih.gov/pubmed/33976213
http://dx.doi.org/10.1038/s41467-021-22989-1