Cargando…
Computational modeling and bioinformatic analyses of functional mutations in drug target genes in Mycobacterium tuberculosis
Tuberculosis (TB) continues to be the leading cause of deaths due to its persistent drug resistance and the consequent ineffectiveness of anti-TB treatment. Recent years witnessed huge amount of sequencing data, revealing mutations responsible for drug resistance. However, the lack of an up-to-date...
Autores principales: | Singh, Pooja, Jamal, Salma, Ahmed, Faraz, Saqib, Najumu, Mehra, Seema, Ali, Waseem, Roy, Deodutta, Ehtesham, Nasreen Z., Hasnain, Seyed E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113780/ https://www.ncbi.nlm.nih.gov/pubmed/34025934 http://dx.doi.org/10.1016/j.csbj.2021.04.034 |
Ejemplares similares
-
The M. tuberculosis Rv1523 Methyltransferase Promotes Drug Resistance Through Methylation-Mediated Cell Wall Remodeling and Modulates Macrophages Immune Responses
por: Ali, Sabeeha, et al.
Publicado: (2021) -
Editorial: Emerging concepts in Mycobacterium tuberculosis pathogenesis: Host-pathogen interaction and stress adaption mechanisms
por: Pandey, Saurabh, et al.
Publicado: (2023) -
Comparative genomic and proteomic analyses of PE/PPE multigene family of Mycobacterium tuberculosis H(37)Rv and H(37)Ra reveal novel and interesting differences with implications in virulence
por: Kohli, Sakshi, et al.
Publicado: (2012) -
Comparative Analyses of Nonpathogenic, Opportunistic, and Totally Pathogenic Mycobacteria Reveal Genomic and Biochemical Variabilities and Highlight the Survival Attributes of Mycobacterium tuberculosis
por: Rahman, Syed Asad, et al.
Publicado: (2014) -
PGRS Domain of Rv0297 of Mycobacterium tuberculosis Is Involved in Modulation of Macrophage Functions to Favor Bacterial Persistence
por: Sharma, Tarina, et al.
Publicado: (2020)