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Stimulation of α7 Nicotinic Acetylcholine Receptor by Nicotine Suppresses Decidual M1 Macrophage Polarization Against Inflammation in Lipopolysaccharide-Induced Preeclampsia-Like Mouse Model

Changes in decidual macrophage polarization affect local inflammatory microenvironment and lead to adverse pregnancy outcomes. However, the regulatory mechanism of macrophage polarization in preeclampsia (PE) remains unclear. In this study, we found that α7nAChR expression was significantly down-reg...

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Detalles Bibliográficos
Autores principales: Han, Xinjia, Li, Wei, Li, Ping, Zheng, Zheng, Lin, Baohua, Zhou, Bei, Guo, Kaimin, He, Ping, Yang, Jinying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113862/
https://www.ncbi.nlm.nih.gov/pubmed/33995360
http://dx.doi.org/10.3389/fimmu.2021.642071