Molecular properties of human guanylate cyclase–activating protein 2 (GCAP2) and its retinal dystrophy–associated variant G157R

In murine and bovine photoreceptors, guanylate cyclase–activating protein 2 (GCAP2) activates retinal guanylate cyclases (GCs) at low Ca(2+) levels, thus contributing to the Ca(2+)/cGMP negative feedback on the cyclase together with its paralog guanylate cyclase–activating protein 1, which has the s...

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Detalles Bibliográficos
Autores principales: Avesani, Anna, Marino, Valerio, Zanzoni, Serena, Koch, Karl-Wilhelm, Dell'Orco, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113879/
https://www.ncbi.nlm.nih.gov/pubmed/33812995
http://dx.doi.org/10.1016/j.jbc.2021.100619

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113879/
https://www.ncbi.nlm.nih.gov/pubmed/33812995
http://dx.doi.org/10.1016/j.jbc.2021.100619

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