Interferon regulatory factor 8 regulates expression of acid ceramidase and infection susceptibility in cystic fibrosis

Most patients with cystic fibrosis (CF) suffer from acute and chronic pulmonary infections with bacterial pathogens, which often determine their life quality and expectancy. Previous studies have demonstrated a downregulation of the acid ceramidase in CF epithelial cells resulting in an increase of...

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Detalles Bibliográficos
Autores principales: Gardner, Aaron Ions, Wu, Yuqing, Verhaegh, Rabea, Liu, Yongjie, Wilker, Barbara, Soddemann, Matthias, Keitsch, Simone, Edwards, Michael J., Haq, Iram J., Kamler, Markus, Becker, Katrin Anne, Brodlie, Malcolm, Gulbins, Erich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113888/
https://www.ncbi.nlm.nih.gov/pubmed/33839155
http://dx.doi.org/10.1016/j.jbc.2021.100650

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