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Innovative Preparation of Biopharmaceuticals Using Transglycosylation Activity of Microbial Endoglycosidases

Most functional biopharmaceuticals such as antibodies are glycoproteins carrying N-linked oligosaccharides (N-glycans). In animal cells, these glycans are generally expressed as heterogeneous glycoforms that are difficult to separate into a pure form. The structure of these glycans directly affects...

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Detalles Bibliográficos
Autores principales: Katoh, Toshihiko, Yamamoto, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Applied Glycoscience 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113915/
https://www.ncbi.nlm.nih.gov/pubmed/34354540
http://dx.doi.org/10.5458/jag.jag.JAG-2020_0013