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Molecular, functional, and pathological aspects of TDP-43 fragmentation

Transactive response DNA binding protein 43 (TDP-43) is a DNA/RNA binding protein involved in transcriptional regulation and RNA processing. It is linked to sporadic and familial amyotrophic lateral sclerosis and frontotemporal lobar degeneration. TDP-43 is predominantly nuclear, but it translocates...

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Detalles Bibliográficos
Autores principales:	Chhangani, Deepak, Martín-Peña, Alfonso, Rincon-Limas, Diego E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113996/ https://www.ncbi.nlm.nih.gov/pubmed/34013172 http://dx.doi.org/10.1016/j.isci.2021.102459

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