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Cure models to estimate time until hospitalization due to COVID-19: A case study in Galicia (NW Spain)
A short introduction to survival analysis and censored data is included in this paper. A thorough literature review in the field of cure models has been done. An overview on the most important and recent approaches on parametric, semiparametric and nonparametric mixture cure models is also included....
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8114025/ https://www.ncbi.nlm.nih.gov/pubmed/34764600 http://dx.doi.org/10.1007/s10489-021-02311-8 |
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author | Pedrosa-Laza, Maria López-Cheda, Ana Cao, Ricardo |
author_facet | Pedrosa-Laza, Maria López-Cheda, Ana Cao, Ricardo |
author_sort | Pedrosa-Laza, Maria |
collection | PubMed |
description | A short introduction to survival analysis and censored data is included in this paper. A thorough literature review in the field of cure models has been done. An overview on the most important and recent approaches on parametric, semiparametric and nonparametric mixture cure models is also included. The main nonparametric and semiparametric approaches were applied to a real time dataset of COVID-19 patients from the first weeks of the epidemic in Galicia (NW Spain). The aim is to model the elapsed time from diagnosis to hospital admission. The main conclusions, as well as the limitations of both the cure models and the dataset, are presented, illustrating the usefulness of cure models in this kind of studies, where the influence of age and sex on the time to hospital admission is shown. |
format | Online Article Text |
id | pubmed-8114025 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-81140252021-05-12 Cure models to estimate time until hospitalization due to COVID-19: A case study in Galicia (NW Spain) Pedrosa-Laza, Maria López-Cheda, Ana Cao, Ricardo Appl Intell (Dordr) Article A short introduction to survival analysis and censored data is included in this paper. A thorough literature review in the field of cure models has been done. An overview on the most important and recent approaches on parametric, semiparametric and nonparametric mixture cure models is also included. The main nonparametric and semiparametric approaches were applied to a real time dataset of COVID-19 patients from the first weeks of the epidemic in Galicia (NW Spain). The aim is to model the elapsed time from diagnosis to hospital admission. The main conclusions, as well as the limitations of both the cure models and the dataset, are presented, illustrating the usefulness of cure models in this kind of studies, where the influence of age and sex on the time to hospital admission is shown. Springer US 2021-05-12 2022 /pmc/articles/PMC8114025/ /pubmed/34764600 http://dx.doi.org/10.1007/s10489-021-02311-8 Text en © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Article Pedrosa-Laza, Maria López-Cheda, Ana Cao, Ricardo Cure models to estimate time until hospitalization due to COVID-19: A case study in Galicia (NW Spain) |
title | Cure models to estimate time until hospitalization due to COVID-19: A case study in Galicia (NW Spain) |
title_full | Cure models to estimate time until hospitalization due to COVID-19: A case study in Galicia (NW Spain) |
title_fullStr | Cure models to estimate time until hospitalization due to COVID-19: A case study in Galicia (NW Spain) |
title_full_unstemmed | Cure models to estimate time until hospitalization due to COVID-19: A case study in Galicia (NW Spain) |
title_short | Cure models to estimate time until hospitalization due to COVID-19: A case study in Galicia (NW Spain) |
title_sort | cure models to estimate time until hospitalization due to covid-19: a case study in galicia (nw spain) |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8114025/ https://www.ncbi.nlm.nih.gov/pubmed/34764600 http://dx.doi.org/10.1007/s10489-021-02311-8 |
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