The Technique of Thyroid Cartilage Scaffold Support Formation for Extrusion-Based Bioprinting

During biofabrication, a tissue scaffold may require temporary support. The aim of this study was to develop an approach of human thyroid cartilage scaffold temporal support formation. The scaffold 3D-model was based on DICOM images. XY plane projections were used to form scaffold supporting part. T...

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Detalles Bibliográficos
Autores principales: Arguchinskaya, N. V., Beketov, E. E., Kisel, A. A., Isaeva, E. V., Osidak, E. O., Domogatsky, S. P., Mikhailovsky, N. V., Sevryukov, F. E., Silantyeva, N. K., Agababyan, T. A., Ivanov, S. A., Shegay, P. V., Kaprin, A. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Whioce Publishing Pte. Ltd. 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8114092/
https://www.ncbi.nlm.nih.gov/pubmed/33997436
http://dx.doi.org/10.18063/ijb.v7i2.348
Descripción
Sumario:During biofabrication, a tissue scaffold may require temporary support. The aim of this study was to develop an approach of human thyroid cartilage scaffold temporal support formation. The scaffold 3D-model was based on DICOM images. XY plane projections were used to form scaffold supporting part. To verify the technique, collagen hydrogel was chosen as the main scaffold component. Gelatin was applied for the supporting part. To test the applicability of the approach, a model of thyroid cartilage scaffold with the support was printed. The scaffold corresponded to a given model, although some discrepancy in geometry was observed during verification by computed tomography.

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