Circular RNA circFADS2 is overexpressed in sepsis and suppresses LPS-induced lung cell apoptosis by inhibiting the maturation of miR-15a-5p

BACKGROUND: Circular RNA circFADS2 plays protective roles in LPS-induced inflammation, which promotes sepsis, suggesting its involvement in sepsis. METHODS: Expression of circFADS2, mature miR-15a-5p, and miR-15a-5p precursor in plasma samples from sepsis patients and healthy controls was determined...

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Detalles Bibliográficos
Autores principales: Hong, Xiaoyang, Li, Shuanglei, Wang, Jie, Zhao, Zhe, Feng, Zhichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8114495/
https://www.ncbi.nlm.nih.gov/pubmed/33980140
http://dx.doi.org/10.1186/s12865-021-00419-7

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