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Deconvolution of cell type-specific drug responses in human tumor tissue with single-cell RNA-seq

BACKGROUND: Preclinical studies require models that recapitulate the cellular diversity of human tumors and provide insight into the drug sensitivities of specific cellular populations. The ideal platform would enable rapid screening of cell type-specific drug sensitivities directly in patient tumor...

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Detalles Bibliográficos
Autores principales:	Zhao, Wenting, Dovas, Athanassios, Spinazzi, Eleonora Francesca, Levitin, Hanna Mendes, Banu, Matei Alexandru, Upadhyayula, Pavan, Sudhakar, Tejaswi, Marie, Tamara, Otten, Marc L., Sisti, Michael B., Bruce, Jeffrey N., Canoll, Peter, Sims, Peter A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8114529/ https://www.ncbi.nlm.nih.gov/pubmed/33975634 http://dx.doi.org/10.1186/s13073-021-00894-y

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