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Population Pharmacokinetics and Initial Dose Optimization of Sirolimus Improving Drug Blood Level for Seizure Control in Pediatric Patients With Tuberous Sclerosis Complex

The purposes of this study were to explore the population pharmacokinetics and initial dose optimization of sirolimus improving drug blood level for seizure control in pediatric patients with tuberous sclerosis complex (TSC). Eighty pediatric patients diagnosed with TSC-related epilepsy were include...

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Detalles Bibliográficos
Autores principales:	Chen, Xiao, Wang, Dongdong, Zhu, Lin, Lu, Jinmiao, Huang, Yidie, Wang, Guangfei, Zhu, Yiqing, Ye, Qiaofeng, Wang, Yi, Xu, Hong, Li, Zhiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8114543/ https://www.ncbi.nlm.nih.gov/pubmed/33995061 http://dx.doi.org/10.3389/fphar.2021.647232

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