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How imputation can mitigate SNP ascertainment Bias
BACKGROUND: Population genetic studies based on genotyped single nucleotide polymorphisms (SNPs) are influenced by a non-random selection of the SNPs included in the used genotyping arrays. The resulting bias in the estimation of allele frequency spectra and population genetics parameters like heter...
Autores principales: | Geibel, Johannes, Reimer, Christian, Pook, Torsten, Weigend, Steffen, Weigend, Annett, Simianer, Henner |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8114708/ https://www.ncbi.nlm.nih.gov/pubmed/33980139 http://dx.doi.org/10.1186/s12864-021-07663-6 |
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