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The degree of astrocyte activation is predictive of the incubation time to prion disease

In neurodegenerative diseases including Alzheimer’s, Parkinson’s and prion diseases, astrocytes acquire disease-associated reactive phenotypes. With growing appreciation of their role in chronic neurodegeneration, the questions whether astrocytes lose their ability to perform homeostatic functions i...

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Detalles Bibliográficos
Autores principales: Makarava, Natallia, Mychko, Olga, Chang, Jennifer Chen-Yu, Molesworth, Kara, Baskakov, Ilia V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8114720/
https://www.ncbi.nlm.nih.gov/pubmed/33980286
http://dx.doi.org/10.1186/s40478-021-01192-9