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Cyclophilin A Plays Potential Roles in a Rat Model of Asthma and Suppression of Immune Response

PURPOSE: Cyclophilin A (CypA) inhibits CD4(+) T cell signal transduction via interleukin-2-inducible T-cell kinase (Itk), a tyrosine kinase required for T helper (Th) 2 cells function. Furthermore, mice with CypA silencing developed allergic diseases associated with increased Th2 cytokines productio...

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Detalles Bibliográficos
Autores principales:	Chen, Cai-Tao, Shan, Chun-Xiao, Ran, Jun, Yin, Lei-Miao, Li, Hai-Yan, Wang, Yu, Xu, Yu-Dong, Guo, Jing-Lei, Shi, Yang-Lin, Chen, Yan-Jiao, Yang, Yong-Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8114824/ https://www.ncbi.nlm.nih.gov/pubmed/33994799 http://dx.doi.org/10.2147/JAA.S308938

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