IFNγ/PD-L1 Signaling Improves the Responsiveness of Anti-PD-1 Therapy in Colorectal Cancer: An in vitro Study

INTRODUCTION: Programmed cell death 1 ligand 1 (PD-L1) can be upregulated in cancer cells via interferon gamma (IFNγ) in the tumor microenvironment. IFNγ/PD-L1 signaling is associated with the response to immune checkpoint blockade in melanoma patients. Our previous investigation indicated that the...

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Detalles Bibliográficos
Autores principales: Yuan, Wenli, Deng, Deyao, Li, Hanyu, Hu, Xinghui, Shang, Xueqin, Hou, Xia, Jiang, Hongchao, He, Hongchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8114827/
https://www.ncbi.nlm.nih.gov/pubmed/33994797
http://dx.doi.org/10.2147/OTT.S294136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8114827/
https://www.ncbi.nlm.nih.gov/pubmed/33994797
http://dx.doi.org/10.2147/OTT.S294136

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