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IFNγ/PD-L1 Signaling Improves the Responsiveness of Anti-PD-1 Therapy in Colorectal Cancer: An in vitro Study
INTRODUCTION: Programmed cell death 1 ligand 1 (PD-L1) can be upregulated in cancer cells via interferon gamma (IFNγ) in the tumor microenvironment. IFNγ/PD-L1 signaling is associated with the response to immune checkpoint blockade in melanoma patients. Our previous investigation indicated that the...
Autores principales: | Yuan, Wenli, Deng, Deyao, Li, Hanyu, Hu, Xinghui, Shang, Xueqin, Hou, Xia, Jiang, Hongchao, He, Hongchun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8114827/ https://www.ncbi.nlm.nih.gov/pubmed/33994797 http://dx.doi.org/10.2147/OTT.S294136 |
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