Hepatomegaly, Elevated Hepatic Enzymes, and Bridging Fibrosis in Patients With Type 1 Diabetes Mellitus

Glycogenic hepatopathy is a rare but reversible condition that includes acute liver dysfunction and hepatomegaly. This occurs due to excessive glycogen accumulation in the hepatocytes. It can occur in patients with poorly controlled type 1 diabetes mellitus. We are reporting a case of a 17-year-old...

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Autores principales: Ahmed, Fahad W, Kirupakaran, Tharaga, Quante, Mara, Smith, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Endocrinology/Diabetes/Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8114958/
https://www.ncbi.nlm.nih.gov/pubmed/33996309
http://dx.doi.org/10.7759/cureus.14446
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author Ahmed, Fahad W
Kirupakaran, Tharaga
Quante, Mara
Smith, Andrew
author_facet Ahmed, Fahad W
Kirupakaran, Tharaga
Quante, Mara
Smith, Andrew
author_sort Ahmed, Fahad W
collection PubMed
description Glycogenic hepatopathy is a rare but reversible condition that includes acute liver dysfunction and hepatomegaly. This occurs due to excessive glycogen accumulation in the hepatocytes. It can occur in patients with poorly controlled type 1 diabetes mellitus. We are reporting a case of a 17-year-old girl who developed liver dysfunction following admission with diabetic ketoacidosis. Ultrasound abdomen confirmed hepatomegaly. However, with improvement in her metabolic control, her liver enzymes and hepatomegaly improved.
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spelling pubmed-81149582021-05-14 Hepatomegaly, Elevated Hepatic Enzymes, and Bridging Fibrosis in Patients With Type 1 Diabetes Mellitus Ahmed, Fahad W Kirupakaran, Tharaga Quante, Mara Smith, Andrew Cureus Endocrinology/Diabetes/Metabolism Glycogenic hepatopathy is a rare but reversible condition that includes acute liver dysfunction and hepatomegaly. This occurs due to excessive glycogen accumulation in the hepatocytes. It can occur in patients with poorly controlled type 1 diabetes mellitus. We are reporting a case of a 17-year-old girl who developed liver dysfunction following admission with diabetic ketoacidosis. Ultrasound abdomen confirmed hepatomegaly. However, with improvement in her metabolic control, her liver enzymes and hepatomegaly improved. Cureus 2021-04-13 /pmc/articles/PMC8114958/ /pubmed/33996309 http://dx.doi.org/10.7759/cureus.14446 Text en Copyright © 2021, Ahmed et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Ahmed, Fahad W
Kirupakaran, Tharaga
Quante, Mara
Smith, Andrew
Hepatomegaly, Elevated Hepatic Enzymes, and Bridging Fibrosis in Patients With Type 1 Diabetes Mellitus
title Hepatomegaly, Elevated Hepatic Enzymes, and Bridging Fibrosis in Patients With Type 1 Diabetes Mellitus
title_full Hepatomegaly, Elevated Hepatic Enzymes, and Bridging Fibrosis in Patients With Type 1 Diabetes Mellitus
title_fullStr Hepatomegaly, Elevated Hepatic Enzymes, and Bridging Fibrosis in Patients With Type 1 Diabetes Mellitus
title_full_unstemmed Hepatomegaly, Elevated Hepatic Enzymes, and Bridging Fibrosis in Patients With Type 1 Diabetes Mellitus
title_short Hepatomegaly, Elevated Hepatic Enzymes, and Bridging Fibrosis in Patients With Type 1 Diabetes Mellitus
title_sort hepatomegaly, elevated hepatic enzymes, and bridging fibrosis in patients with type 1 diabetes mellitus
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8114958/
https://www.ncbi.nlm.nih.gov/pubmed/33996309
http://dx.doi.org/10.7759/cureus.14446
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