The effects of inhibition of fatty acid amide hydrolase (FAAH) by JNJ-42165279 in social anxiety disorder: a double-blind, randomized, placebo-controlled proof-of-concept study

JNJ-42165279 is a selective inhibitor of fatty acid amide hydrolase (FAAH), the enzyme responsible for the degradation of fatty acid amides (FAA) including anandamide (AEA), palmitoylethanolamide (PEA), and N-oleoylethanolamide (OEA). We assessed the efficacy, safety, tolerability, pharmacokinetics,...

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Detalles Bibliográficos
Autores principales: Schmidt, Mark E., Liebowitz, Michael R., Stein, Murray B., Grunfeld, Jennifer, Van Hove, Ilse, Simmons, W. Kyle, Van Der Ark, Peter, Palmer, James A., Saad, Ziad S., Pemberton, Darrel J., Van Nueten, Luc, Drevets, Wayne C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115178/
https://www.ncbi.nlm.nih.gov/pubmed/33070154
http://dx.doi.org/10.1038/s41386-020-00888-1

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