Antioxidant treatment ameliorates prefrontal hypomyelination and cognitive deficits in a rat model of schizophrenia

Cognitive dysfunction in schizophrenia (SZ) is thought to arise from neurodevelopmental abnormalities that include interneuron hypomyelination in the prefrontal cortex (PFC). Here we report that RNA-sequencing of the medial (m)PFC of the APO-SUS rat model with SZ-relevant cognitive inflexibility rev...

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Detalles Bibliográficos
Autores principales: Maas, D. A., Eijsink, V. D., van Hulten, J. A., Panic, R., De Weerd, P., Homberg, J. R., Vallès, A., Nait-Oumesmar, B., Martens, G. J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115238/
https://www.ncbi.nlm.nih.gov/pubmed/33564104
http://dx.doi.org/10.1038/s41386-021-00964-0

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