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Relationship Between Blood Pressure and Incident Cardiovascular Disease: Linear and Nonlinear Mendelian Randomization Analyses
Observational studies exploring whether there is a nonlinear effect of blood pressure on cardiovascular disease (CVD) risk are hindered by confounding. This limitation can be overcome by leveraging randomly allocated genetic variants in nonlinear Mendelian randomization analyses. Based on their asso...
Autores principales: | Malik, Rainer, Georgakis, Marios K., Vujkovic, Marijana, Damrauer, Scott M., Elliott, Paul, Karhunen, Ville, Giontella, Alice, Fava, Cristiano, Hellwege, Jacklyn N., Shuey, Megan M., Edwards, Todd L., Rogne, Tormod, Åsvold, Bjørn O., Brumpton, Ben M., Burgess, Stephen, Dichgans, Martin, Gill, Dipender |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115430/ https://www.ncbi.nlm.nih.gov/pubmed/33813844 http://dx.doi.org/10.1161/HYPERTENSIONAHA.120.16534 |
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