Cargando…

Apatinib suppresses lung cancer stem-like cells by complex interplay between β-catenin signaling and mitochondrial ROS accumulation

The abnormal activation of Wnt/β-catenin signaling plays a critical role in the development of lung cancer, which is also important in the generation and maintenance of lung cancer stem cell (CSC). CSCs have unique capabilities to resist anticancer therapy, seed recurrent tumors, and disseminate to...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Jianyun, Li, Xiaoting, Liang, Chunhua, Zhou, Xu, Ge, Miaomiao, Chen, Yue, Jin, Jianliang, Yin, Juan, Xu, Haie, Xie, Chunfeng, Zhong, Caiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115647/
https://www.ncbi.nlm.nih.gov/pubmed/33980809
http://dx.doi.org/10.1038/s41420-021-00480-6