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The oncological relevance of fragile sites in cancer

Recent developments in sequencing the cancer genome have provided the first in-depth mapping of structural variants (SV) across 38 tumour types. Sixteen signatures of structural variants have been proposed which broadly characterise the variation seen across cancer types. One signature shows increas...

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Detalles Bibliográficos
Autores principales: Simpson, Benjamin S., Pye, Hayley, Whitaker, Hayley C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115686/
https://www.ncbi.nlm.nih.gov/pubmed/33980983
http://dx.doi.org/10.1038/s42003-021-02020-5

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