Cargando…
Landscape of allele-specific transcription factor binding in the human genome
Sequence variants in gene regulatory regions alter gene expression and contribute to phenotypes of individual cells and the whole organism, including disease susceptibility and progression. Single-nucleotide variants in enhancers or promoters may affect gene transcription by altering transcription f...
Autores principales: | Abramov, Sergey, Boytsov, Alexandr, Bykova, Daria, Penzar, Dmitry D., Yevshin, Ivan, Kolmykov, Semyon K., Fridman, Marina V., Favorov, Alexander V., Vorontsov, Ilya E., Baulin, Eugene, Kolpakov, Fedor, Makeev, Vsevolod J., Kulakovskiy, Ivan V. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115691/ https://www.ncbi.nlm.nih.gov/pubmed/33980847 http://dx.doi.org/10.1038/s41467-021-23007-0 |
Ejemplares similares
-
ANANASTRA: annotation and enrichment analysis of allele-specific transcription factor binding at SNPs
por: Boytsov, Alexandr, et al.
Publicado: (2022) -
GTRD: an integrated view of transcription regulation
por: Kolmykov, Semyon, et al.
Publicado: (2020) -
Genome-wide map of human and mouse transcription factor binding sites aggregated from ChIP-Seq data
por: Vorontsov, Ilya E., et al.
Publicado: (2018) -
What Do Neighbors Tell About You: The Local Context of Cis-Regulatory Modules Complicates Prediction of Regulatory Variants
por: Penzar, Dmitry D., et al.
Publicado: (2019) -
Positional weight matrices have sufficient prediction power for analysis of noncoding variants
por: Boytsov, Alexandr, et al.
Publicado: (2022)