Cargando…

Auditory evoked potentials: Differences by sex, race, and menstrual cycle and correlations with common psychoacoustical tasks

Auditory brainstem responses (ABRs) and auditory middle-latency responses (AMLRs) to a click stimulus were measured in about 100 subjects. Of interest were the sex differences in those auditory evoked potentials (AEPs), the correlations between the various AEP measures, and the correlations between...

Descripción completa

Detalles Bibliográficos
Autores principales: McFadden, Dennis, Champlin, Craig A., Pho, Michelle H., Pasanen, Edward G., Maloney, Mindy M., Leshikar, Erin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115856/
https://www.ncbi.nlm.nih.gov/pubmed/33979393
http://dx.doi.org/10.1371/journal.pone.0251363
_version_ 1783691276708741120
author McFadden, Dennis
Champlin, Craig A.
Pho, Michelle H.
Pasanen, Edward G.
Maloney, Mindy M.
Leshikar, Erin M.
author_facet McFadden, Dennis
Champlin, Craig A.
Pho, Michelle H.
Pasanen, Edward G.
Maloney, Mindy M.
Leshikar, Erin M.
author_sort McFadden, Dennis
collection PubMed
description Auditory brainstem responses (ABRs) and auditory middle-latency responses (AMLRs) to a click stimulus were measured in about 100 subjects. Of interest were the sex differences in those auditory evoked potentials (AEPs), the correlations between the various AEP measures, and the correlations between the AEP measures and measures of otoacoustic emissions (OAEs) and behavioral performance also measured on the same subjects. Also of interest was how the menstrual cycle affected the various AEP measures. Most ABR measures and several AMLR measures exhibited sex differences, and many of the former were substantial. The sex differences tended to be larger for latency than for amplitude of the waves, and they tended to be larger for a weak click stimulus than for a strong click. The largest sex difference was for Wave-V latency (effect size ~1.2). When subjects were dichotomized into Non-Whites and Whites, the race differences in AEPs were small within sex. However, sex and race interacted so that the sex differences often were larger for the White subjects than for the Non-White subjects, particularly for the latency measures. Contrary to the literature, no AEP measures differed markedly across the menstrual cycle. Correlations between various AEP measures, and between AEP and OAE measures, were small and showed no consistent patterns across sex or race categories. Performance on seven common psychoacoustical tasks was only weakly correlated with individual AEP measures (just as was true for the OAEs also measured on these subjects). AMLR Wave Pa unexpectedly did not show the decrease in latency and increase in amplitude typically observed for AEPs when click level was varied from 40 to 70 dB nHL (normal Hearing Level). For the majority of the measures, the variability of the distribution of scores was greater for the males than for the females.
format Online
Article
Text
id pubmed-8115856
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-81158562021-05-24 Auditory evoked potentials: Differences by sex, race, and menstrual cycle and correlations with common psychoacoustical tasks McFadden, Dennis Champlin, Craig A. Pho, Michelle H. Pasanen, Edward G. Maloney, Mindy M. Leshikar, Erin M. PLoS One Research Article Auditory brainstem responses (ABRs) and auditory middle-latency responses (AMLRs) to a click stimulus were measured in about 100 subjects. Of interest were the sex differences in those auditory evoked potentials (AEPs), the correlations between the various AEP measures, and the correlations between the AEP measures and measures of otoacoustic emissions (OAEs) and behavioral performance also measured on the same subjects. Also of interest was how the menstrual cycle affected the various AEP measures. Most ABR measures and several AMLR measures exhibited sex differences, and many of the former were substantial. The sex differences tended to be larger for latency than for amplitude of the waves, and they tended to be larger for a weak click stimulus than for a strong click. The largest sex difference was for Wave-V latency (effect size ~1.2). When subjects were dichotomized into Non-Whites and Whites, the race differences in AEPs were small within sex. However, sex and race interacted so that the sex differences often were larger for the White subjects than for the Non-White subjects, particularly for the latency measures. Contrary to the literature, no AEP measures differed markedly across the menstrual cycle. Correlations between various AEP measures, and between AEP and OAE measures, were small and showed no consistent patterns across sex or race categories. Performance on seven common psychoacoustical tasks was only weakly correlated with individual AEP measures (just as was true for the OAEs also measured on these subjects). AMLR Wave Pa unexpectedly did not show the decrease in latency and increase in amplitude typically observed for AEPs when click level was varied from 40 to 70 dB nHL (normal Hearing Level). For the majority of the measures, the variability of the distribution of scores was greater for the males than for the females. Public Library of Science 2021-05-12 /pmc/articles/PMC8115856/ /pubmed/33979393 http://dx.doi.org/10.1371/journal.pone.0251363 Text en © 2021 McFadden et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
McFadden, Dennis
Champlin, Craig A.
Pho, Michelle H.
Pasanen, Edward G.
Maloney, Mindy M.
Leshikar, Erin M.
Auditory evoked potentials: Differences by sex, race, and menstrual cycle and correlations with common psychoacoustical tasks
title Auditory evoked potentials: Differences by sex, race, and menstrual cycle and correlations with common psychoacoustical tasks
title_full Auditory evoked potentials: Differences by sex, race, and menstrual cycle and correlations with common psychoacoustical tasks
title_fullStr Auditory evoked potentials: Differences by sex, race, and menstrual cycle and correlations with common psychoacoustical tasks
title_full_unstemmed Auditory evoked potentials: Differences by sex, race, and menstrual cycle and correlations with common psychoacoustical tasks
title_short Auditory evoked potentials: Differences by sex, race, and menstrual cycle and correlations with common psychoacoustical tasks
title_sort auditory evoked potentials: differences by sex, race, and menstrual cycle and correlations with common psychoacoustical tasks
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115856/
https://www.ncbi.nlm.nih.gov/pubmed/33979393
http://dx.doi.org/10.1371/journal.pone.0251363
work_keys_str_mv AT mcfaddendennis auditoryevokedpotentialsdifferencesbysexraceandmenstrualcycleandcorrelationswithcommonpsychoacousticaltasks
AT champlincraiga auditoryevokedpotentialsdifferencesbysexraceandmenstrualcycleandcorrelationswithcommonpsychoacousticaltasks
AT phomichelleh auditoryevokedpotentialsdifferencesbysexraceandmenstrualcycleandcorrelationswithcommonpsychoacousticaltasks
AT pasanenedwardg auditoryevokedpotentialsdifferencesbysexraceandmenstrualcycleandcorrelationswithcommonpsychoacousticaltasks
AT maloneymindym auditoryevokedpotentialsdifferencesbysexraceandmenstrualcycleandcorrelationswithcommonpsychoacousticaltasks
AT leshikarerinm auditoryevokedpotentialsdifferencesbysexraceandmenstrualcycleandcorrelationswithcommonpsychoacousticaltasks