Cargando…

LIM domain only 1: an oncogenic transcription cofactor contributing to the tumorigenesis of multiple cancer types

The LIM domain only 1 (LMO1) gene belongs to the LMO family of genes that encodes a group of transcriptional cofactors. This group of transcriptional cofactors regulates gene transcription by acting as a key “connector” or “scaffold” in transcription complexes. All LMOs, including LMO1, are importan...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Guo-Fa, Du, Li-Qin, Zhang, Lei, Jia, You-Chao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2021
Materias:	Review Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116020/ https://www.ncbi.nlm.nih.gov/pubmed/33870932 http://dx.doi.org/10.1097/CM9.0000000000001487

Ejemplares similares

The LIM-domain only protein 4 contributes to lung epithelial cell proliferation but is not essential for tumor progression
por: Holik, Aliaksei Z., et al.
Publicado: (2015)

Deficiency of the LIM-Only Protein FHL2 Reduces Intestinal Tumorigenesis in Apc Mutant Mice
por: Labalette, Charlotte, et al.
Publicado: (2010)

LIM Domain Only 2 Regulates Endothelial Proliferation, Angiogenesis, and Tissue Regeneration
por: Meng, Shu, et al.
Publicado: (2016)

The LIM-only protein, LMO4, and the LIM domain-binding protein, LDB1, expression in squamous cell carcinomas of the oral cavity
por: Mizunuma, H, et al.
Publicado: (2003)

LIM Domain Only-2 (LMO2) Induces T-Cell Leukemia by Two Distinct Pathways
por: Smith, Stephen, et al.
Publicado: (2014)

Recent advances in searching c-Myc transcriptional cofactors during tumorigenesis
por: Caforio, Matteo, et al.
Publicado: (2018)

Targeting nitrative stress for attenuating cisplatin-induced downregulation of cochlear LIM domain only 4 and ototoxicity
por: Jamesdaniel, Samson, et al.
Publicado: (2016)

Analysis of the Drosophila Ajuba LIM protein defines functions for distinct LIM domains
por: Rauskolb, Cordelia, et al.
Publicado: (2022)

LIM only 4 is overexpressed in late stage pancreas cancer
por: Yu, Jun, et al.
Publicado: (2008)

The PET and LIM1-2 domains of testin contribute to intramolecular and homodimeric interactions
por: Sala, Stefano, et al.
Publicado: (2017)

The Cytoplasmic LIM Domain Protein Espinas Contributes to Photoreceptor Layer Selection in the Visual System
por: Fernández-Pineda, Alejandra, et al.
Publicado: (2020)

LIM domain only 2 over-expression in prostate stromal cells facilitates prostate cancer progression through paracrine of Interleukin-11
por: Jiang, Chen-Yi, et al.
Publicado: (2016)

The Co-factor of LIM Domains (CLIM/LDB/NLI) Maintains Basal Mammary Epithelial Stem Cells and Promotes Breast Tumorigenesis
por: Salmans, Michael L., et al.
Publicado: (2014)

Contribution of the LIM Domain and Nebulin-Repeats to the Interaction of Lasp-2 with Actin Filaments and Focal Adhesions
por: Nakagawa, Hiroyuki, et al.
Publicado: (2009)

Deficiency in the LIM-only protein Fhl2 impairs skin wound healing
por: Wixler, Viktor, et al.
Publicado: (2007)

SIGLa: an adaptable LIMS for multiple laboratories
por: Melo, Alexandre, et al.
Publicado: (2010)

p53 Represses Transcription of RING Finger LIM Domain-Binding Protein RLIM through Sp1
por: Kong, Xiangtao, et al.
Publicado: (2013)

A LIM Domain Protein from Tobacco Involved in Actin-Bundling and Histone Gene Transcription
por: Moes, Danièle, et al.
Publicado: (2013)

Transcriptional regulation and ubiquitination-dependent regulation of HnRNPK oncogenic function in prostate tumorigenesis
por: Wu, Huan-Lei, et al.
Publicado: (2021)

The LIM-Only Protein FHL2 is involved in Autophagy to Regulate the Development of Skeletal Muscle Cell
por: Liu, Zihao, et al.
Publicado: (2019)

Four and a Half LIM Domains 2 (FHL2) Contribute to the Epithelial Ovarian Cancer Carcinogenesis
por: Wang, Chen, et al.
Publicado: (2020)

LIM-Only Protein 4 (LMO4) and LIM Domain Binding Protein 1 (LDB1) Promote Growth and Metastasis of Human Head and Neck Cancer (LMO4 and LDB1 in Head and Neck Cancer)
por: Simonik, Elizabeth A., et al.
Publicado: (2016)

LIM1 contributes to the malignant potential of endometrial cancer
por: Kato, Hiroaki, et al.
Publicado: (2023)

Biosynthesis of cofactor‐activatable iron‐only nitrogenase in Saccharomyces cerevisiae
por: López‐Torrejón, Gema, et al.
Publicado: (2021)

The transcription factor ATF3 acts as an oncogene in mouse mammary tumorigenesis
por: Wang, Aijin, et al.
Publicado: (2008)

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
por: DeNicola, Gina M., et al.
Publicado: (2011)

A requirement for Lim domain binding protein 1 in erythropoiesis
por: Li, LiQi, et al.
Publicado: (2010)

LIM Homeobox Domain 2 Is Required for Corneal Epithelial Homeostasis
por: Sartaj, Rachel, et al.
Publicado: (2016)

The Roles of the LIM Domain Proteins in Drosophila Cardiac and Hematopoietic Morphogenesis
por: She, Meihua, et al.
Publicado: (2021)

PDZ and LIM Domain-Encoding Genes: Their Role in Cancer Development
por: Jiang, Xinyuan, et al.
Publicado: (2023)

The LIM-only protein FHL2 interacts with β-catenin and promotes differentiation of mouse myoblasts
por: Martin, Bernd, et al.
Publicado: (2002)

The LIM-Only Protein FHL2 Attenuates Lung Inflammation during Bleomycin-Induced Fibrosis
por: Alnajar, Abdulaleem, et al.
Publicado: (2013)

Structure of the Catalytic Domain of EZH2 Reveals Conformational Plasticity in Cofactor and Substrate Binding Sites and Explains Oncogenic Mutations
por: Wu, Hong, et al.
Publicado: (2013)

A high-throughput screen identifies inhibitors of the interaction between the oncogenic transcription factor ERG and the cofactor EWS
por: Nicholas, Taylor R., et al.
Publicado: (2020)

Oncogenic role of mortalin contributes to ovarian tumorigenesis by activating the MAPK–ERK pathway
por: Hu, Yingying, et al.
Publicado: (2016)

Transcription factor CASZ1 increases an oncogenic transcriptional process in tumorigenesis and progression of glioma cells
por: Mao, Chaofu, et al.
Publicado: (2022)

LIM Domain Kinases as Potential Therapeutic Targets for Neurofibromatosis Type 2
por: Petrilli, Alejandra, et al.
Publicado: (2013)

Requirement of LIM domains for the transient accumulation of paxillin at damaged stress fibres
por: Watanabe-Nakayama, Takahiro, et al.
Publicado: (2013)

PDZ and LIM Domain-Encoding Genes: Molecular Interactions and their Role in Development
por: te Velthuis, Aartjan J. W., et al.
Publicado: (2007)

Hypothalamic Rax(+) tanycytes contribute to tissue repair and tumorigenesis upon oncogene activation in mice
por: Mu, Wenhui, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_d24dnh1ms41p990ku9addn90im