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Membrane transporter dimerization driven by differential lipid solvation energetics of dissociated and associated states
Over two-thirds of integral membrane proteins of known structure assemble into oligomers. Yet, the forces that drive the association of these proteins remain to be delineated, as the lipid bilayer is a solvent environment that is both structurally and chemically complex. In this study, we reveal how...
Autores principales: | Chadda, Rahul, Bernhardt, Nathan, Kelley, Elizabeth G, Teixeira, Susana CM, Griffith, Kacie, Gil-Ley, Alejandro, Öztürk, Tuğba N, Hughes, Lauren E, Forsythe, Ana, Krishnamani, Venkatramanan, Faraldo-Gómez, José D, Robertson, Janice L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116059/ https://www.ncbi.nlm.nih.gov/pubmed/33825681 http://dx.doi.org/10.7554/eLife.63288 |
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