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Role of Tryptophan 38 in Loading Substrate Chain into the Active-site Tunnel of Cellobiohydrolase I from Trichoderma reesei
Cellobiohydrolase I from Trichoderma reesei ( Tr Cel7A) is one of the best-studied cellulases, exhibiting high activity towards crystalline cellulose. Tryptophan residues at subsites -7 and -4 (Trp40 and Trp38 respectively) are located at the entrance and middle of the tunnel-like active site of Tr...
Autores principales: | Nakamura, Akihiko, Kanazawa, Takashi, Furuta, Tadaomi, Sakurai, Minoru, Saloheimo, Markku, Samejima, Masahiro, Koivula, Anu, Igarashi, Kiyohiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Applied Glycoscience
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116176/ https://www.ncbi.nlm.nih.gov/pubmed/34354542 http://dx.doi.org/10.5458/jag.jag.JAG-2020_0014 |
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