Open-label phase II study evaluating safety and efficacy of the non-steroidal farnesoid X receptor agonist PX-104 in non-alcoholic fatty liver disease

BACKGROUND: The PX-104 is an oral non-steroidal agonist for the farnesoid X receptor (FXR), a key regulator of bile acid (BA), glucose and lipid homeostasis. AIMS AND METHODS: This single center, proof of concept study evaluated the efficacy, safety and tolerability of PX-104 in non-diabetic NAFLD p...

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Detalles Bibliográficos
Autores principales: Traussnigg, Stefan, Halilbasic, Emina, Hofer, Harald, Munda, Petra, Stojakovic, Tatjana, Fauler, Günter, Kashofer, Karl, Krssak, Martin, Wolzt, Michael, Trauner, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116226/
https://www.ncbi.nlm.nih.gov/pubmed/32930860
http://dx.doi.org/10.1007/s00508-020-01735-5

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