CSF3R T618I, SETBP1 G870S, SRSF2 P95H, and ASXL1 Q780* tetramutation co-contribute to myeloblast transformation in a chronic neutrophilic leukemia

Chronic neutrophilic leukemia (CNL) is a rare but serious myeloid malignancy. In a review of reported cases for WHO-defined CNL, CSF3R mutation is found in about 90% cases and confirmed as the molecular basis of CNL. Concurrent mutations are observed in CSF3R-mutated CNL patients, including ASXL1, S...

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Detalles Bibliográficos
Autores principales: Qian, Yi, Chen, Yan, Li, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116236/
https://www.ncbi.nlm.nih.gov/pubmed/33822276
http://dx.doi.org/10.1007/s00277-021-04491-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116236/
https://www.ncbi.nlm.nih.gov/pubmed/33822276
http://dx.doi.org/10.1007/s00277-021-04491-2

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