An analysis of the Kozak consensus in retinal genes and its relevance to gene therapy

PURPOSE: The classic Kozak consensus is a critical genetic element included in gene therapy transgenes to encourage the translation of the therapeutic coding sequence. Despite optimizations of other transgene elements, the Kozak consensus has not yet been considered for potential tissue-specific seq...

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Detalles Bibliográficos
Autores principales: McClements, Michelle E., Butt, Anum, Piotter, Elena, Peddle, Caroline F., MacLaren, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116250/
https://www.ncbi.nlm.nih.gov/pubmed/34012226

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