CBP/p300 HAT maintains the gene network critical for β cell identity and functional maturity

Loss of β cell identity and functional immaturity are thought to be involved in β cell failure in type 2 diabetes. CREB-binding protein (CBP) and its paralogue p300 act as multifunctional transcriptional co-activators and histone acetyltransferases (HAT) with extensive biological functions. However,...

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Detalles Bibliográficos
Autores principales: Zhang, Linlin, Sheng, Chunxiang, Zhou, Feiye, Zhu, Kecheng, Wang, Shushu, Liu, Qianqian, Yuan, Miaomiao, Xu, Zhaoqian, Liu, Yun, Lu, Jieli, Liu, Jianmin, Zhou, Libin, Wang, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116341/
https://www.ncbi.nlm.nih.gov/pubmed/33980820
http://dx.doi.org/10.1038/s41419-021-03761-1

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