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Activation of Neurogenesis in Multipotent Stem Cells Cultured In Vitro and in the Spinal Cord Tissue After Severe Injury by Inhibition of Glycogen Synthase Kinase-3
The inhibition of glycogen synthase kinase-3 (GSK-3) can induce neurogenesis, and the associated activation of Wnt/β-catenin signaling via GSK-3 inhibition may represent a means to promote motor function recovery following spinal cord injury (SCI) via increased astrocyte migration, reduced astrocyte...
Autores principales: | Rodriguez-Jimenez, Francisco Javier, Vilches, Angel, Perez-Arago, Maria Amparo, Clemente, Eleonora, Roman, Raquel, Leal, Juliette, Castro, Ana Artero, Fustero, Santos, Moreno-Manzano, Victoria, Jendelova, Pavla, Stojkovic, Miodrag, Erceg, Slaven |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116371/ https://www.ncbi.nlm.nih.gov/pubmed/33000422 http://dx.doi.org/10.1007/s13311-020-00928-0 |
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