Desmoglein-4 Deficiency Exacerbates Psoriasiform Dermatitis in Rats While Psoriasis Patients Displayed a Decreased Gene Expression of DSG4

Desmogleins are involved in cell adhesion conferring structural skin integrity. However, their role in inflammation has been barely studied, and whether desmoglein-4 modulates psoriasis lesions is completely unknown. In this study, we assessed the impact of desmoglein-4 deficiency on the severity of...

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Detalles Bibliográficos
Autores principales: Moreno-Sosa, Tamara, Sánchez, María Belén, Pietrobon, Elisa Olivia, Fernandez-Muñoz, Juan Manuel, Zoppino, Felipe Carlos Martín, Neira, Flavia Judith, Germanó, María José, Cargnelutti, Diego Esteban, Innocenti, Alicia Carolina, Jahn, Graciela Alma, Valdez, Susana Ruth, Mackern-Oberti, Juan Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116535/
https://www.ncbi.nlm.nih.gov/pubmed/33995349
http://dx.doi.org/10.3389/fimmu.2021.625617

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