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Bronchiectasis—Could Immunonutrition Have a Role to Play in Future Management?

Bronchiectasis is a chronic condition in which areas of the bronchial tubes become permanently widened predisposing the lungs to infection. Bronchiectasis is an age-associated disease with the highest prevalence in people older than 75 years. While the prevalence of bronchiectasis is higher in males...

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Autores principales: Derbyshire, Emma J., Calder, Philip C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116598/
https://www.ncbi.nlm.nih.gov/pubmed/33996875
http://dx.doi.org/10.3389/fnut.2021.652410
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author Derbyshire, Emma J.
Calder, Philip C.
author_facet Derbyshire, Emma J.
Calder, Philip C.
author_sort Derbyshire, Emma J.
collection PubMed
description Bronchiectasis is a chronic condition in which areas of the bronchial tubes become permanently widened predisposing the lungs to infection. Bronchiectasis is an age-associated disease with the highest prevalence in people older than 75 years. While the prevalence of bronchiectasis is higher in males, disease is more severe in females who have a poorer prognosis. The overall prevalence of the disease is thought to be rising. Its aetiology is multi-faceted, but a compromised immune system is now thought to play a central role in the pathology of this disease. Research has begun to study the role of malnutrition and certain nutrients—vitamin D and zinc—along with the role of the lung microbiome in relation to the management of bronchiectasis. Given this, the present mini review sets out to provide an overview of the state-of-the-art within the field, identify research gaps and pave the way for future developments and research investment within this field.
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spelling pubmed-81165982021-05-14 Bronchiectasis—Could Immunonutrition Have a Role to Play in Future Management? Derbyshire, Emma J. Calder, Philip C. Front Nutr Nutrition Bronchiectasis is a chronic condition in which areas of the bronchial tubes become permanently widened predisposing the lungs to infection. Bronchiectasis is an age-associated disease with the highest prevalence in people older than 75 years. While the prevalence of bronchiectasis is higher in males, disease is more severe in females who have a poorer prognosis. The overall prevalence of the disease is thought to be rising. Its aetiology is multi-faceted, but a compromised immune system is now thought to play a central role in the pathology of this disease. Research has begun to study the role of malnutrition and certain nutrients—vitamin D and zinc—along with the role of the lung microbiome in relation to the management of bronchiectasis. Given this, the present mini review sets out to provide an overview of the state-of-the-art within the field, identify research gaps and pave the way for future developments and research investment within this field. Frontiers Media S.A. 2021-04-29 /pmc/articles/PMC8116598/ /pubmed/33996875 http://dx.doi.org/10.3389/fnut.2021.652410 Text en Copyright © 2021 Derbyshire and Calder. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Nutrition
Derbyshire, Emma J.
Calder, Philip C.
Bronchiectasis—Could Immunonutrition Have a Role to Play in Future Management?
title Bronchiectasis—Could Immunonutrition Have a Role to Play in Future Management?
title_full Bronchiectasis—Could Immunonutrition Have a Role to Play in Future Management?
title_fullStr Bronchiectasis—Could Immunonutrition Have a Role to Play in Future Management?
title_full_unstemmed Bronchiectasis—Could Immunonutrition Have a Role to Play in Future Management?
title_short Bronchiectasis—Could Immunonutrition Have a Role to Play in Future Management?
title_sort bronchiectasis—could immunonutrition have a role to play in future management?
topic Nutrition
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116598/
https://www.ncbi.nlm.nih.gov/pubmed/33996875
http://dx.doi.org/10.3389/fnut.2021.652410
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