The CD39(+) HBV surface protein-targeted CAR-T and personalized tumor-reactive CD8(+) T cells exhibit potent anti-HCC activity

CD39, expressed by tumor-infiltrating lymphocytes (TILs), is a marker to identify tumor-reactive T cells, which is frequently associated with stronger antitumor activity than bystander T cells in a variety of malignancies. Therefore, CD39 could be a promising marker for identifying the active antitu...

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Detalles Bibliográficos
Autores principales: Zou, Fan, Tan, Jizhou, Liu, Ting, Liu, Bingfeng, Tang, Yaping, Zhang, Hui, Li, Jiaping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116602/
https://www.ncbi.nlm.nih.gov/pubmed/33484968
http://dx.doi.org/10.1016/j.ymthe.2021.01.021

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