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Quaternary ammonium salts based on (-)-borneol as effective inhibitors of influenza virus

A series of compounds containing a 1,7,7-trimethylbicyclo[2.2.1]heptane fragment were evaluated for their antiviral activity against influenza A virus strain A/Puerto Rico/8/34 (H1N1) in vitro. The most potent antiviral compound proved to be a quaternary ammonium salt based on (-)-borneol, 10a. In i...

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Detalles Bibliográficos
Autores principales: Sokolova, Anastasiya S., Yarovaya, Olga I., Baranova, Darya V., Galochkina, Anastasia V., Shtro, Anna A., Kireeva, Marina V., Borisevich, Sophia S., Gatilov, Yuriy V., Zarubaev, Vladimir V., Salakhutdinov, Nariman F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116641/
https://www.ncbi.nlm.nih.gov/pubmed/33983502
http://dx.doi.org/10.1007/s00705-021-05102-1