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Prevalence of High Risk HPV in HIV-Infected Women From Belém, Pará, Amazon Region of Brazil: A Cross-Sectional Study

Human papillomavirus (HPV) is the most common sexually transmitted infection in the world. Several studies have shown a higher prevalence of HPV infection in HIV-infected women. The aim of this study was to determine the prevalence and the genotype diversity of HPV infection in HIV-infected women. F...

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Autores principales: Monteiro, Jacqueline Cortinhas, Fonseca, Ricardo Roberto de Souza, Ferreira, Tuane Carolina de Sousa, Rodrigues, Luana Lorena Silva, da Silva, Andreza Reis Brasil, Gomes, Samara Tatielle, Silvestre, Rodrigo Vellasco Duarte, Silva, Andréa Nazaré Monteiro Rangel, Pamplona, Ilze, Vallinoto, Antonio Carlos Rosário, Ishak, Ricardo, Machado, Luiz Fernando Almeida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116653/
https://www.ncbi.nlm.nih.gov/pubmed/33996727
http://dx.doi.org/10.3389/fpubh.2021.649152
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author Monteiro, Jacqueline Cortinhas
Fonseca, Ricardo Roberto de Souza
Ferreira, Tuane Carolina de Sousa
Rodrigues, Luana Lorena Silva
da Silva, Andreza Reis Brasil
Gomes, Samara Tatielle
Silvestre, Rodrigo Vellasco Duarte
Silva, Andréa Nazaré Monteiro Rangel
Pamplona, Ilze
Vallinoto, Antonio Carlos Rosário
Ishak, Ricardo
Machado, Luiz Fernando Almeida
author_facet Monteiro, Jacqueline Cortinhas
Fonseca, Ricardo Roberto de Souza
Ferreira, Tuane Carolina de Sousa
Rodrigues, Luana Lorena Silva
da Silva, Andreza Reis Brasil
Gomes, Samara Tatielle
Silvestre, Rodrigo Vellasco Duarte
Silva, Andréa Nazaré Monteiro Rangel
Pamplona, Ilze
Vallinoto, Antonio Carlos Rosário
Ishak, Ricardo
Machado, Luiz Fernando Almeida
author_sort Monteiro, Jacqueline Cortinhas
collection PubMed
description Human papillomavirus (HPV) is the most common sexually transmitted infection in the world. Several studies have shown a higher prevalence of HPV infection in HIV-infected women. The aim of this study was to determine the prevalence and the genotype diversity of HPV infection in HIV-infected women. From April 2010 to December 2012 cervical specimens were collected from 169 HIV-infected women who screening for cervical cancer at Reference Unit in Belém. The detection of HPV infection was performed by nested PCR and HPV type was performed using a commercial system. The prevalence of HPV infection was 63.3%. Of the 47 genotyped samples, 40.4% was found positive for high risk-HPV 16 and 12.8% for high risk-HPV 52. HPV infection was predominant in the group of women with no incidence of cytological abnormalities and more prevalent in women of reproductive age, unmarried, low education level, and who reported use condoms during sexual intercourse. It was observed an association between HPV infection and independent variables, such as condom use, multiple sexual partners, and history of sexually transmitted diseases. High-risk types of HPV infection were prevalent in our study. Infection with multiple high-risk HPV genotypes may potentiate the development of cervical cancer in HIV-infected women.
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spelling pubmed-81166532021-05-14 Prevalence of High Risk HPV in HIV-Infected Women From Belém, Pará, Amazon Region of Brazil: A Cross-Sectional Study Monteiro, Jacqueline Cortinhas Fonseca, Ricardo Roberto de Souza Ferreira, Tuane Carolina de Sousa Rodrigues, Luana Lorena Silva da Silva, Andreza Reis Brasil Gomes, Samara Tatielle Silvestre, Rodrigo Vellasco Duarte Silva, Andréa Nazaré Monteiro Rangel Pamplona, Ilze Vallinoto, Antonio Carlos Rosário Ishak, Ricardo Machado, Luiz Fernando Almeida Front Public Health Public Health Human papillomavirus (HPV) is the most common sexually transmitted infection in the world. Several studies have shown a higher prevalence of HPV infection in HIV-infected women. The aim of this study was to determine the prevalence and the genotype diversity of HPV infection in HIV-infected women. From April 2010 to December 2012 cervical specimens were collected from 169 HIV-infected women who screening for cervical cancer at Reference Unit in Belém. The detection of HPV infection was performed by nested PCR and HPV type was performed using a commercial system. The prevalence of HPV infection was 63.3%. Of the 47 genotyped samples, 40.4% was found positive for high risk-HPV 16 and 12.8% for high risk-HPV 52. HPV infection was predominant in the group of women with no incidence of cytological abnormalities and more prevalent in women of reproductive age, unmarried, low education level, and who reported use condoms during sexual intercourse. It was observed an association between HPV infection and independent variables, such as condom use, multiple sexual partners, and history of sexually transmitted diseases. High-risk types of HPV infection were prevalent in our study. Infection with multiple high-risk HPV genotypes may potentiate the development of cervical cancer in HIV-infected women. Frontiers Media S.A. 2021-04-29 /pmc/articles/PMC8116653/ /pubmed/33996727 http://dx.doi.org/10.3389/fpubh.2021.649152 Text en Copyright © 2021 Monteiro, Fonseca, Ferreira, Rodrigues, da Silva, Gomes, Silvestre, Silva, Pamplona, Vallinoto, Ishak and Machado. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Public Health
Monteiro, Jacqueline Cortinhas
Fonseca, Ricardo Roberto de Souza
Ferreira, Tuane Carolina de Sousa
Rodrigues, Luana Lorena Silva
da Silva, Andreza Reis Brasil
Gomes, Samara Tatielle
Silvestre, Rodrigo Vellasco Duarte
Silva, Andréa Nazaré Monteiro Rangel
Pamplona, Ilze
Vallinoto, Antonio Carlos Rosário
Ishak, Ricardo
Machado, Luiz Fernando Almeida
Prevalence of High Risk HPV in HIV-Infected Women From Belém, Pará, Amazon Region of Brazil: A Cross-Sectional Study
title Prevalence of High Risk HPV in HIV-Infected Women From Belém, Pará, Amazon Region of Brazil: A Cross-Sectional Study
title_full Prevalence of High Risk HPV in HIV-Infected Women From Belém, Pará, Amazon Region of Brazil: A Cross-Sectional Study
title_fullStr Prevalence of High Risk HPV in HIV-Infected Women From Belém, Pará, Amazon Region of Brazil: A Cross-Sectional Study
title_full_unstemmed Prevalence of High Risk HPV in HIV-Infected Women From Belém, Pará, Amazon Region of Brazil: A Cross-Sectional Study
title_short Prevalence of High Risk HPV in HIV-Infected Women From Belém, Pará, Amazon Region of Brazil: A Cross-Sectional Study
title_sort prevalence of high risk hpv in hiv-infected women from belém, pará, amazon region of brazil: a cross-sectional study
topic Public Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116653/
https://www.ncbi.nlm.nih.gov/pubmed/33996727
http://dx.doi.org/10.3389/fpubh.2021.649152
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