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A Set of Eight Key Questions Helps to Classify Common Vestibular Disorders—Results From the DizzyReg Patient Registry

Precise history taking is the key to develop a first assumption on the diagnosis of vestibular disorders. Particularly in the primary care setting, algorithms are needed, which are based on a small number of questions and variables only to guide appropriate diagnostic decisions. The aim of this stud...

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Autores principales: Strobl, Ralf, Grözinger, Michael, Zwergal, Andreas, Huppert, Doreen, Filippopulos, Filipp, Grill, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116658/
https://www.ncbi.nlm.nih.gov/pubmed/33995265
http://dx.doi.org/10.3389/fneur.2021.670944
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author Strobl, Ralf
Grözinger, Michael
Zwergal, Andreas
Huppert, Doreen
Filippopulos, Filipp
Grill, Eva
author_facet Strobl, Ralf
Grözinger, Michael
Zwergal, Andreas
Huppert, Doreen
Filippopulos, Filipp
Grill, Eva
author_sort Strobl, Ralf
collection PubMed
description Precise history taking is the key to develop a first assumption on the diagnosis of vestibular disorders. Particularly in the primary care setting, algorithms are needed, which are based on a small number of questions and variables only to guide appropriate diagnostic decisions. The aim of this study is to identify a set of such key variables that can be used for preliminary classification of the most common vestibular disorders. A four-step approach was implemented to achieve this aim: (1) we conducted an online expert survey to collect variables that are meaningful for medical history taking, (2) we used qualitative content analysis to structure these variables, (3) we identified matching variables of the patient registry of the German Center for Vertigo and Balance Disorders, and (4) we used classification trees to build a classification model based on these identified variables and to analyze if and how these variables contribute to the classification of common vestibular disorders. We included a total of 1,066 patients with seven common vestibular disorders (mean age of 51.1 years, SD = 15.3, 56% female). Functional dizziness was the most frequent diagnosis (32.5%), followed by vestibular migraine (20.2%) and Menière's disease (13.3%). Using classification trees, we identified eight key variables which can differentiate the seven vestibular disorders with an accuracy of almost 50%. The key questions comprised attack duration, rotational vertigo, hearing problems, turning in bed as a trigger, doing sport or heavy household chores as a trigger, age, having problems with walking in the dark, and vomiting. The presented algorithm showed a high-face validity and can be helpful for taking initial medical history in patients with vertigo and dizziness. Further research is required to evaluate if the identified algorithm can be applied in the primary care setting and to evaluate its external validity.
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spelling pubmed-81166582021-05-14 A Set of Eight Key Questions Helps to Classify Common Vestibular Disorders—Results From the DizzyReg Patient Registry Strobl, Ralf Grözinger, Michael Zwergal, Andreas Huppert, Doreen Filippopulos, Filipp Grill, Eva Front Neurol Neurology Precise history taking is the key to develop a first assumption on the diagnosis of vestibular disorders. Particularly in the primary care setting, algorithms are needed, which are based on a small number of questions and variables only to guide appropriate diagnostic decisions. The aim of this study is to identify a set of such key variables that can be used for preliminary classification of the most common vestibular disorders. A four-step approach was implemented to achieve this aim: (1) we conducted an online expert survey to collect variables that are meaningful for medical history taking, (2) we used qualitative content analysis to structure these variables, (3) we identified matching variables of the patient registry of the German Center for Vertigo and Balance Disorders, and (4) we used classification trees to build a classification model based on these identified variables and to analyze if and how these variables contribute to the classification of common vestibular disorders. We included a total of 1,066 patients with seven common vestibular disorders (mean age of 51.1 years, SD = 15.3, 56% female). Functional dizziness was the most frequent diagnosis (32.5%), followed by vestibular migraine (20.2%) and Menière's disease (13.3%). Using classification trees, we identified eight key variables which can differentiate the seven vestibular disorders with an accuracy of almost 50%. The key questions comprised attack duration, rotational vertigo, hearing problems, turning in bed as a trigger, doing sport or heavy household chores as a trigger, age, having problems with walking in the dark, and vomiting. The presented algorithm showed a high-face validity and can be helpful for taking initial medical history in patients with vertigo and dizziness. Further research is required to evaluate if the identified algorithm can be applied in the primary care setting and to evaluate its external validity. Frontiers Media S.A. 2021-04-29 /pmc/articles/PMC8116658/ /pubmed/33995265 http://dx.doi.org/10.3389/fneur.2021.670944 Text en Copyright © 2021 Strobl, Grözinger, Zwergal, Huppert, Filippopulos and Grill. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Strobl, Ralf
Grözinger, Michael
Zwergal, Andreas
Huppert, Doreen
Filippopulos, Filipp
Grill, Eva
A Set of Eight Key Questions Helps to Classify Common Vestibular Disorders—Results From the DizzyReg Patient Registry
title A Set of Eight Key Questions Helps to Classify Common Vestibular Disorders—Results From the DizzyReg Patient Registry
title_full A Set of Eight Key Questions Helps to Classify Common Vestibular Disorders—Results From the DizzyReg Patient Registry
title_fullStr A Set of Eight Key Questions Helps to Classify Common Vestibular Disorders—Results From the DizzyReg Patient Registry
title_full_unstemmed A Set of Eight Key Questions Helps to Classify Common Vestibular Disorders—Results From the DizzyReg Patient Registry
title_short A Set of Eight Key Questions Helps to Classify Common Vestibular Disorders—Results From the DizzyReg Patient Registry
title_sort set of eight key questions helps to classify common vestibular disorders—results from the dizzyreg patient registry
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116658/
https://www.ncbi.nlm.nih.gov/pubmed/33995265
http://dx.doi.org/10.3389/fneur.2021.670944
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