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Read trimming has minimal effect on bacterial SNP-calling accuracy
Read alignment is the central step of many analytic pipelines that perform variant calling. To reduce error, it is common practice to pre-process raw sequencing reads to remove low-quality bases and residual adapter contamination, a procedure collectively known as ‘trimming’. Trimming is widely assu...
Autor principal: | Bush, Stephen J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Microbiology Society
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116680/ https://www.ncbi.nlm.nih.gov/pubmed/33332257 http://dx.doi.org/10.1099/mgen.0.000434 |
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